Basic Information
| Drug ID | DDPD00967 |
|
| Drug Name | Desloratadine | |
| Molecular Weight | 310.821 | |
| Molecular Formula | C19H19ClN2 | |
| CAS Number | 100643-71-8 | |
| SMILES | ClC1=CC2=C(C=C1)C(=C1CCNCC1)C1=C(CC2)C=CC=N1 | |
| External Links | ||
| DRUGBANK | DB00967 | |
| T3DB | T3D4557 | |
| PubChem Compound | 124087 | |
| PDR | 334 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.2 | - | 3.2 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 50.0 | h | 50 | h | DRUGBANK | |
| Eliminate Route | 87.0 | % | ~87 | % | DRUGBANK | |
| Protein Binding | 84.5 | % | 82-87 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for infants | 1.0 | mg/day | 1 | mg/day | PO, oral | Clarinex | desloratadine | PDR |
| Max dose for children | 5.0 | mg/day | 5 | mg/day | PO, oral | Clarinex | desloratadine | PDR |
| Max dose for children | 2.5 | mg/day | 2.5 | mg/day | PO, oral | Clarinex | desloratadine | PDR |
| Max dose for children | 1.25 | mg/day | 1.25 | mg/day | PO, oral | Clarinex | desloratadine | PDR |
| Max dose for adolescents | 5.0 | mg/day | 5 | mg/day | PO, oral | Clarinex | desloratadine | PDR |
| Max dose for adults | 5.0 | mg/day | 5 | mg/day | PO, oral | Clarinex | desloratadine | PDR |
| Max dose for geriatric | 5.0 | mg/day | 5 | mg/day | PO, oral | Clarinex | desloratadine | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1