Basic Information
| Drug ID | DDPD00964 |
|
| Drug Name | Apraclonidine | |
| Molecular Weight | 245.109 | |
| Molecular Formula | C9H10Cl2N4 | |
| CAS Number | 66711-21-5 | |
| SMILES | NC1=CC(Cl)=C(NC2=NCCN2)C(Cl)=C1 | |
| External Links | ||
| DRUGBANK | DB00964 | |
| PubChem Compound | 2216 | |
| PDR | 1095 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.4 | - | 1.4 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| C Max | 0.90 | ng/ml | 0.9 | ng/ml | ophthalmic administration; | DRUGBANK |
| Half-life | 8.0 | h | 8 | h | DRUGBANK | |
| Protein Binding | 98.7 | % | 98.7 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 6.0 | drop/day | 6 | drop/day | ophthalmic administration | Iopidine 0.5% Ophthalmic Solution | apraclonidine hydrochloride | PDR |
| Max dose for adults | 2.0 | drop/day | 2 | drop/day | ophthalmic administration | Iopidine 0.5% Ophthalmic Solution | apraclonidine hydrochloride | PDR |
| Max dose for elderly | 6.0 | drop/day | 6 | drop/day | ophthalmic administration | Iopidine 0.5% Ophthalmic Solution | apraclonidine hydrochloride | PDR |
| Max dose for elderly | 2.0 | drop/day | 2 | drop/day | ophthalmic administration | Iopidine 0.5% Ophthalmic Solution | apraclonidine hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1