Basic Information
| Drug ID | DDPD00963 |
|
| Drug Name | Bromfenac | |
| Molecular Weight | 334.165 | |
| Molecular Formula | C15H12BrNO3 | |
| CAS Number | 91714-94-2 | |
| SMILES | NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1 | |
| External Links | ||
| DRUGBANK | DB00963 | |
| PubChem Compound | 60726 | |
| PDR | 3118 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.4 | - | 3.4 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.0780 | L/h/kg | 1.3 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.11 | L/kg | 0.11 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 2.6 | h | 2.6 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 1.0 | drop/day | 1 | drop/day | ophthalmic administration | Prolensa | bromfenac sodium | PDR |
| Max dose for adults | 2.0 | drop/day | 2 | drop/day | ophthalmic administration | Prolensa | bromfenac sodium | PDR |
| Max dose for geriatric | 1.0 | drop/day | 1 | drop/day | ophthalmic administration | Prolensa | bromfenac sodium | PDR |
| Max dose for geriatric | 2.0 | drop/day | 2 | drop/day | ophthalmic administration | Prolensa | bromfenac sodium | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1