Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00957 ...
Drug Name Norgestimate
Molecular Weight 369.4971
Molecular Formula C23H31NO3
CAS Number 35189-28-7
SMILES [H][C@@]12CC[C@@](OC(C)=O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CC\C(C=C3CC[C@@]21[H])=N/O
External Links
DRUGBANK DB00957
PubChem Compound 6540478

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Melting Point 216.0 ℃ 216 ℃ PhysProp

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
AUC 16.1 ng.h/ml 16.1 ng.h/ml PO, oral; Active metabolite; DRUGBANK
AUC 49.9 ng.h/ml 49.9 ng.h/ml PO, oral; Active metabolite; DRUGBANK
C Max 1.8 ng/ml 1.82 ng/ml PO, oral; Active metabolite; DRUGBANK
C Max 2.8 ng/ml 2.79 ng/ml PO, oral; Active metabolite; DRUGBANK
T Max 1.3 h 0.5-2 h PO, oral; DRUGBANK
T Max 1.5 h 1.5 h PO, oral; Active metabolite; DRUGBANK
T Max 1.7 h 1.7 h PO, oral; Active metabolite; DRUGBANK
Half-life 21.0 h 12-30 h DRUGBANK
Half-life 36.4 h 36.4±10.2 h DRUGBANK
Eliminate Route 47.0 % 45-49 % Urinary excretion; DRUGBANK
Eliminate Route 32.5 % 16-49 % Faeces excretion; DRUGBANK
Protein Binding 97.0 % >97 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1