Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00955 ...
Drug Name Netilmicin
Molecular Weight 475.587
Molecular Formula C21H41N5O7
CAS Number 56391-56-1
SMILES CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@](C)(O)[C@H](NC)[C@H]1O
External Links
DRUGBANK DB00955
PubChem Compound 441306

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P -3.0 - -3.0 - DRUGBANK
Water Solubility 100000.0 mg/L 100 mg/ml DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Absorption 100.0 % 100 % IM,intramuscular injection; DRUGBANK
T Max 0.75 h 0.5-1 h IM,intramuscular injection; DRUGBANK
Metabolic 80.0 % 80 % Urinary excretion; DRUGBANK
Clearance 0.0330 L/h/kg 0.55 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.0730 L/kg 0.073 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 2.5 h 2.5 h DRUGBANK
Half-life 3.2 h 3.2 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1