Basic Information

Drug ID DDPD00949 ...
Drug Name Felbamate
Molecular Weight 238.2399
Molecular Formula C11H14N2O4
CAS Number 25451-15-4
SMILES NC(=O)OCC(COC(N)=O)C1=CC=CC=C1
External Links
DRUGBANK DB00949
T3DB T3D2937
PubChem Compound 3331
PDR 1781
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 0.3 - 0.3 - DRUGBANK
Melting Point 151.5 151.5 PhysProp

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Absorption 90.0 % >90 % DRUGBANK
Clearance 0.0260 L/h/kg 26±3 ml/h/kg Single dose; DRUGBANK
Clearance 0.0300 L/h/kg 30±8 ml/h/kg Multiple dose; DRUGBANK
Volume of Distribution 0.76 L/kg 756±82 mL/kg DRUGBANK
Half-life 21.5 h 20-23 h DRUGBANK
Toxicity LD50 5000.0 mg/kg 5000.0 mg/kg PO, oral; Rattus, Rat; DRUGBANK
Toxicity LD50 5000.0 mg/kg 5000.0 mg/kg PO, oral; Rattus, Rat; T3DB
Protein Binding 27.5 % 20-36 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1