Basic Information
| Drug ID | DDPD00949 |
|
| Drug Name | Felbamate | |
| Molecular Weight | 238.2399 | |
| Molecular Formula | C11H14N2O4 | |
| CAS Number | 25451-15-4 | |
| SMILES | NC(=O)OCC(COC(N)=O)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00949 | |
| T3DB | T3D2937 | |
| PubChem Compound | 3331 | |
| PDR | 1781 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.3 | - | 0.3 | - | DRUGBANK |
| Melting Point | 151.5 | ℃ | 151.5 | ℃ | PhysProp |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 90.0 | % | >90 | % | DRUGBANK | |
| Clearance | 0.0260 | L/h/kg | 26±3 | ml/h/kg | Single dose; | DRUGBANK | Clearance | 0.0300 | L/h/kg | 30±8 | ml/h/kg | Multiple dose; | DRUGBANK |
| Volume of Distribution | 0.76 | L/kg | 756±82 | mL/kg | DRUGBANK | |
| Half-life | 21.5 | h | 20-23 | h | DRUGBANK | |
| Toxicity LD50 | 5000.0 | mg/kg | 5000.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 5000.0 | mg/kg | 5000.0 | mg/kg | PO, oral; Rattus, Rat; | T3DB |
| Protein Binding | 27.5 | % | 20-36 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1