Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Caco-2 Permeability | -4.79 | - | -4.79 | - | ADME Research, USCD |
| Log P | 2.26 | - | 2.26 | - | HANSCH,C ET AL. (1995) |
| Boiling Point | 211.0 | ℃ | 211 | ℃ | PhysProp |
| Melting Point | 158.0 | ℃ | 158 | ℃ | PhysProp |
| Water Solubility | 2240.0 | mg/L | 2240 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| pKa | 2.97 | - | 2.97 | - | SERJEANT,EP & DEMPSEY,B (1979) |
| Log S | -1.82 | - | -1.82 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Toxicity LD50 | 891.0 | mg/kg | 891.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 891.0 | mg/kg | 891.0 | mg/kg | PO, oral; Rattus, Rat; | T3DB |
| Toxicity LC50 | 0.90 | mg/L/h | >900 | mg/m3/1h | inhalation, IH; Rattus, Rat; | DRUGBANK | Toxicity LC50 | 0.90 | mg/L/h | 900.0 | mg/m3/1h | inhalation, IH; Rattus, Rat; | T3DB |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1