Basic Information
| Drug ID | DDPD00932 |
|
| Drug Name | Tipranavir | |
| Molecular Weight | 602.664 | |
| Molecular Formula | C31H33F3N2O5S | |
| CAS Number | 174484-41-4 | |
| SMILES | [H][C@@](CC)(C1=CC(NS(=O)(=O)C2=NC=C(C=C2)C(F)(F)F)=CC=C1)C1=C(O)C[C@@](CCC)(CCC2=CC=CC=C2)OC1=O | |
| External Links | ||
| DRUGBANK | DB00932 | |
| PubChem Compound | 54682461 | |
| PDR | 1740 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 6.9 | - | 6.9 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 5.5 | h | 5-6 | h | DRUGBANK | |
| Toxicity LD50 | 5000.0 | mg/kg | 5000.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
| Protein Binding | 99.9 | % | >99.9 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 28.0 | mg/kg/day | 28 | mg/kg/day | PO, oral | Aptivus | tipranavir | PDR |
| Max dose for adolescents | 28.0 | mg/kg/day | 28 | mg/kg/day | PO, oral | Aptivus | tipranavir | PDR |
| Max dose for adults | 1000.0 | mg/day | 1000 | mg/day | PO, oral | Aptivus | tipranavir | PDR |
| Max dose for geriatric | 1000.0 | mg/day | 1000 | mg/day | PO, oral | Aptivus | tipranavir | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1