Basic Information
| Drug ID | DDPD00919 |
|
| Drug Name | Spectinomycin | |
| Molecular Weight | 332.3496 | |
| Molecular Formula | C14H24N2O7 | |
| CAS Number | 1695-77-8 | |
| SMILES | [H][C@@]12O[C@H](C)CC(=O)[C@]1(O)O[C@]1([H])[C@@H](NC)[C@@H](O)[C@@H](NC)[C@H](O)[C@@]1([H])O2 | |
| External Links | ||
| DRUGBANK | DB00919 | |
| PubChem Compound | 15541 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -2.3 | - | -2.3 | - | DRUGBANK |
| pKa | 6.95 | - | 6.95 | - | MERCK INDEX (1996); pKa1 |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 100.0 | % | 100 | % | IM,intramuscular injection; | DRUGBANK |
| Clearance | 0.0594 | L/h/kg | 0.99 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.13 | L/kg | 0.13 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 2.0 | h | 1-3 | h | normal renal function; patients; | DRUGBANK | Half-life | 20.0 | h | 10-30 | h | RD, renal impairment, Renal disease，including uremia; patients; | DRUGBANK | Half-life | 1.8 | h | 1.8 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 | 5000.0 | mg/kg | >5000 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1