Basic Information
| Drug ID | DDPD00918 |
|
| Drug Name | Almotriptan | |
| Molecular Weight | 335.464 | |
| Molecular Formula | C17H25N3O2S | |
| CAS Number | 154323-57-6 | |
| SMILES | CN(C)CCC1=CNC2=C1C=C(CS(=O)(=O)N1CCCC1)C=C2 | |
| External Links | ||
| DRUGBANK | DB00918 | |
| T3DB | T3D2931 | |
| PubChem Compound | 123606 | |
| PDR | 2126 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.6 | - | 1.6 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.53 | L/h/kg | 8.9 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 190.0 | L | 180-200 | L | DRUGBANK | Volume of Distribution | 2.2 | L/kg | 2.2 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 3.5 | h | 3-4 | h | DRUGBANK | Half-life | 3.4 | h | 3.4 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route | 75.0 | % | ~75 | % | Urinary excretion; PO, oral; | DRUGBANK | Eliminate Route | 13.0 | % | ~13 | % | Faeces excretion; PO, oral; | DRUGBANK | Eliminate Route | 40.0 | % | ~40 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 35.0 | % | 35 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 25.0 | mg/day | 25 | mg/day | PO, oral | Axert | almotriptan malate | PDR |
| Max dose for adolescents | 25.0 | mg/day | 25 | mg/day | PO, oral | Axert | almotriptan malate | PDR |
| Max dose for adults | 25.0 | mg/day | 25 | mg/day | PO, oral | Axert | almotriptan malate | PDR |
| Max dose for elderly | 25.0 | mg/day | 25 | mg/day | PO, oral | Axert | almotriptan malate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1