Basic Information
| Drug ID | DDPD00896 |
|
| Drug Name | Rimexolone | |
| Molecular Weight | 370.533 | |
| Molecular Formula | C24H34O3 | |
| CAS Number | 49697-38-3 | |
| SMILES | [H][C@@]12C[C@@H](C)[C@](C)(C(=O)CC)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C | |
| External Links | ||
| DRUGBANK | DB00896 | |
| PubChem Compound | 5311412 | |
| PDR | 1079 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 4.2 | - | 4.2 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Metabolic | 80.0 | % | >80 | % | Faeces excretion; | DRUGBANK |
| Half-life | 1.5 | h | 1-2 | h | DRUGBANK | |
| Eliminate Route | 80.0 | % | >80 | % | Faeces excretion; intravenous injection, IV; Rattus, Rat; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 2.0 | drops/eye | 2 | drops/eye | ophthalmic administration; up to 1 week | Vexol | rimexolone | PDR |
| Max dose for elderly | 2.0 | drops/eye | 2 | drops/eye | ophthalmic administration; up to 1 week | Vexol | rimexolone | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1