Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00891 ...
Drug Name Sulfapyridine
Molecular Weight 249.289
Molecular Formula C11H11N3O2S
CAS Number 144-83-2
SMILES NC1=CC=C(C=C1)S(=O)(=O)NC1=CC=CC=N1
External Links
DRUGBANK DB00891
PubChem Compound 5336

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 0.35 - 0.35 - HANSCH,C ET AL. (1995)
Melting Point 192.0 ℃ 192 ℃ PhysProp
Water Solubility 268.0 mg/L 268 mg/L YALKOWSKY,SH & DANNENFELSER,RM 1992)
pKa 8.43 - 8.43 - PERRIN,DD (1965)
Log S -2.7 - -2.7 - ADME Research, USCD

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Absorption 70.0 % 60-80 % DRUGBANK
Half-life 10.0 h 6-14 h DRUGBANK
Toxicity LD50 15800.0 mg/kg 15800.0 mg/kg PO, oral; Rattus, Rat; DRUGBANK
Protein Binding 50.0 % ~50 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1