Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 7.2 | - | 7.2 | - | DRUGBANK |
| Melting Point | 117.25 | ℃ | 116.5-118 | ℃ | Allen, R.E., Palopoli, F.P., Schumann, E.L. and Van Carnpen, M.G. Jr.; US. Patent 2,914,563; November 24, 1959; assigned to The Wrn. S. Merrell Company. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 144.0 | h | 5-7 | day | DRUGBANK | |
| Toxicity LD50 | 1700.0 | mg/kg | 1700.0 | mg/kg | PO, oral; mouse; | DRUGBANK | Toxicity LD50 | 5750.0 | mg/kg | 5750.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 1700.0 | mg/kg | 1700.0 | mg/kg | PO, oral; mouse; | T3DB | Toxicity LD50 | 5750.0 | mg/kg | 5750.0 | mg/kg | PO, oral; Rattus, Rat; | T3DB |
| Eliminate Route | 8.0 | % | ~8 | % | Urinary excretion; PO, oral; human, homo sapiens; | DRUGBANK | Eliminate Route | 42.0 | % | ~42 | % | Faeces excretion; PO, oral; human, homo sapiens; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1