Basic Information
| Drug ID | DDPD00876 |
|
| Drug Name | Eprosartan | |
| Molecular Weight | 424.513 | |
| Molecular Formula | C23H24N2O4S | |
| CAS Number | 133040-01-4 | |
| SMILES | CCCCC1=NC=C(\C=C(/CC2=CC=CS2)C(O)=O)N1CC1=CC=C(C=C1)C(O)=O | |
| External Links | ||
| DRUGBANK | DB00876 | |
| PubChem Compound | 5281037 | |
| PDR | 28 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.9 | - | 3.9 | - | DRUGBANK |
| Melting Point | 249.0 | ℃ | 248-250 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 13.0 | % | 13 | % | Oral single dose; | DRUGBANK |
| Metabolic | 2.0 | % | <2 | % | Urinary excretion; PO, oral; | DRUGBANK |
| Clearance | 0.11 | L/h/kg | 1.9 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.17 | L/kg | 0.17 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 7.0 | h | 5-9 | h | elimination half-life; PO, oral; | DRUGBANK | Half-life | 2.1 | h | 2.1 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 98.0 | % | ~98 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 900.0 | mg/day | 900 | mg/day | PO, oral | Teveten | eprosartan mesylate | PDR |
| Max dose for elderly | 900.0 | mg/day | 900 | mg/day | PO, oral | Teveten | eprosartan mesylate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1