Drug ID | DDPD00872 |
|
Drug Name | Conivaptan | |
Molecular Weight | 498.5744 | |
Molecular Formula | C32H26N4O2 | |
CAS Number | 210101-16-9 | |
SMILES | CC1=NC2=C(CCN(C(=O)C3=CC=C(NC(=O)C4=CC=CC=C4C4=CC=CC=C4)C=C3)C3=CC=CC=C23)N1 | |
External Links | ||
DRUGBANK | DB00872 | |
PubChem Compound | 151171 | |
PDR | 2107 | |
Drugs.com | Drugs.com Drug Page |
Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
---|---|---|---|---|---|
Log P | 6.3 | - | 6.3 | - | DRUGBANK |
Water Solubility | 150.0 | mg/L | 0.15 | mg/ml | DRUGBANK |
Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
---|---|---|---|---|---|---|
Clearance | 0.18 | L/h/kg | 3 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Volume of Distribution | 0.76 | L/kg | 0.76 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Half-life | 5.0 | h | 5 | h | DRUGBANK | Half-life | 6.7 | h | 6.7 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Protein Binding | 99.0 | % | 99 | % | DRUGBANK |
Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
---|---|---|---|---|---|---|---|---|
Max dose for adults | 20.0 | mg/dose | 20 | mg/dose | intravenous injection, IV | Vaprisol | conivaptan hydrochloride | PDR |
Max dose for adults | 40.0 | mg/day | 40 | mg/day | intravenous infusion, iv in drop | Vaprisol | conivaptan hydrochloride | PDR |
Max dose for elderly | 20.0 | mg/dose | 20 | mg/dose | intravenous injection, IV | Vaprisol | conivaptan hydrochloride | PDR |
Max dose for elderly | 40.0 | mg/day | 40 | mg/day | intravenous infusion, iv in drop | Vaprisol | conivaptan hydrochloride | PDR |