Basic Information
| Drug ID | DDPD00868 |
|
| Drug Name | Benzonatate | |
| Molecular Weight | 603.7419 | |
| Molecular Formula | C30H53NO11 | |
| CAS Number | 104-31-4 | |
| SMILES | CCCCNC1=CC=C(C=C1)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOC | |
| External Links | ||
| DRUGBANK | DB00868 | |
| PubChem Compound | 7699 | |
| PDR | 1327 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.45 | - | 2.45 | - | HANSCH,C ET AL. (1995) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| C Max | 1063.0 | ng/ml | 1063±460 | ng/ml | PO, oral; | DRUGBANK |
| Half-life | 1.0 | h | 1.01±0.41 | h | PO, oral; normal,healthy; Asian; | DRUGBANK |
| Toxicity LD50 | 400.0 | mg/kg | 400.0 | mg/kg | PO, oral; mouse; | DRUGBANK | Toxicity LD50 | 100.0 | mg/kg | 100.0 | mg/kg | subcutaneous injection, SC; mouse; | DRUGBANK |
| Toxicity TDLo | 51.0 | mg/kg | 51.0 | mg/kg | PO, oral; Male, men; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 600.0 | mg/day | 600 | mg/day | PO, oral | Tessalon | benzonatate | PDR |
| Max dose for adolescents | 600.0 | mg/day | 600 | mg/day | PO, oral | Tessalon | benzonatate | PDR |
| Max dose for adults | 600.0 | mg/day | 600 | mg/day | PO, oral | Tessalon | benzonatate | PDR |
| Max dose for geriatric | 600.0 | mg/day | 600 | mg/day | PO, oral | Tessalon | benzonatate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1