Basic Information
| Drug ID | DDPD00865 |
|
| Drug Name | Benzphetamine | |
| Molecular Weight | 239.3553 | |
| Molecular Formula | C17H21N | |
| CAS Number | 156-08-1 | |
| SMILES | C[C@@H](CC1=CC=CC=C1)N(C)CC1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00865 | |
| T3DB | T3D2919 | |
| PubChem Compound | 5311017 | |
| PDR | 3868 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 4.1 | - | 4.1 | - | DRUGBANK |
| Melting Point | 129.5 | ℃ | 129-130 | ℃ | Heinzelman, R.V. and Aspergren, B.D.; US. Patent 2,789,138; April 16,1957; assigned to The Upjohn Company. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 23.5 | h | 16-31 | h | DRUGBANK | |
| Toxicity LD50 | 160.0 | mg/kg | 160.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 160.0 | mg/kg | 160.0 | mg/kg | PO, oral; Rattus, Rat; | T3DB |
| Protein Binding | 87.0 | % | 75-99 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adolescents | 150.0 | mg/day | 150 | mg/day | PO, oral | Regimex | benzphetamine hydrochloride | PDR |
| Max dose for adults | 150.0 | mg/day | 150 | mg/day | PO, oral | Regimex | benzphetamine hydrochloride | PDR |
| Max dose for elderly | 150.0 | mg/day | 150 | mg/day | PO, oral | Regimex | benzphetamine hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1