Basic Information
| Drug ID | DDPD00855 |
|
| Drug Name | Aminolevulinic acid | |
| Molecular Weight | 131.1299 | |
| Molecular Formula | C5H9NO3 | |
| CAS Number | 106-60-5 | |
| SMILES | NCC(=O)CCC(O)=O | |
| External Links | ||
| DRUGBANK | DB00855 | |
| T3DB | T3D4273 | |
| PubChem Compound | 137 | |
| PDR | 1572 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -1.5 | - | -1.5 | - | DRUGBANK |
| Melting Point | 157.0 | ℃ | 156-158 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 55.0 | % | 50-60 | % | DRUGBANK | |
| Clearance | 0.11 | L/h/kg | 1.88 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.12 | L/kg | 0.12 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 0.70 | h | 0.7±0.18 | h | PO, oral; | DRUGBANK | Half-life | 0.83 | h | 0.83±0.05 | h | intravenous injection, IV; | DRUGBANK | Half-life | 0.83 | h | 0.83 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 20.0 | mg/kg | 20 | mg/kg | Liquid | Levulan | aminolevulinic acid hydrochloride | PDR |
| Max dose for adults | 1.0 | appLication | 1 | appLication | skin/dermal; nan | Levulan | aminolevulinic acid hydrochloride | PDR |
| Max dose for adults | 20.0 | cm2/dose | 20 | cm2/dose | gel | Levulan | aminolevulinic acid hydrochloride | PDR |
| Max dose for adults | 2000.0 | mg | 2 | g | gel | Levulan | aminolevulinic acid hydrochloride | PDR |
| Max dose for geriatric | 20.0 | mg/kg | 20 | mg/kg | Liquid | Levulan | aminolevulinic acid hydrochloride | PDR |
| Max dose for geriatric | 1.0 | application | 1 | application | skin/dermal; nan | Levulan | aminolevulinic acid hydrochloride | PDR |
| Max dose for geriatric | 20.0 | cm2/dose | 20 | cm2/dose | gel | Levulan | aminolevulinic acid hydrochloride | PDR |
| Max dose for geriatric | 2000.0 | mg | 2 | g | gel | Levulan | aminolevulinic acid hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1