Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00841 ...
Drug Name Dobutamine
Molecular Weight 301.3801
Molecular Formula C18H23NO3
CAS Number 34368-04-2
SMILES CC(CCC1=CC=C(O)C=C1)NCCC1=CC(O)=C(O)C=C1
External Links
DRUGBANK DB00841
PubChem Compound 36811
PDR 3159
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 3.6 - 3.6 - DRUGBANK
Melting Point 185.0 ℃ 184-186 ℃ J. Mills, R. R. Tuttle, U.S. Patent 3,987,200 (1976).

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 6.9 L/h/kg 115 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 0.0333 h 2 min DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for neonates 28.8 mg/kg/day 20 mcg/kg/minute intravenous infusion, iv in drop Dobutamine Hydrochloride in 5% Dextrose dobutamine hydrochloride PDR
Max dose for infants 28.8 mg/kg/day 20 mcg/kg/min intravenous infusion, iv in drop Dobutamine Hydrochloride in 5% Dextrose dobutamine hydrochloride PDR
Max dose for infants 57.6 mg/kg/day 40 mcg/kg/min intravenous infusion, iv in drop; rarely Dobutamine Hydrochloride in 5% Dextrose dobutamine hydrochloride PDR
Max dose for children 28.8 mg/kg/day 20 mcg/kg/minute intravenous infusion, iv in drop Dobutamine Hydrochloride in 5% Dextrose dobutamine hydrochloride PDR
Max dose for children 57.6 mg/kg/day 40 mcg/kg/minute intravenous infusion, iv in drop; rarely Dobutamine Hydrochloride in 5% Dextrose dobutamine hydrochloride PDR
Max dose for adolescents 28.8 mg/kg/day 20 mcg/kg/minute intravenous infusion, iv in drop Dobutamine Hydrochloride in 5% Dextrose dobutamine hydrochloride PDR
Max dose for adolescents 57.6 mg/kg/day 40 mcg/kg/minute intravenous infusion, iv in drop; rarely Dobutamine Hydrochloride in 5% Dextrose dobutamine hydrochloride PDR
Max dose for adults 28.8 mg/kg/day 20 mcg/kg/min intravenous infusion, iv in drop Dobutamine Hydrochloride in 5% Dextrose dobutamine hydrochloride PDR
Max dose for adults 57.6 mg/kg/day 40 mcg/kg/min intravenous infusion, iv in drop; rarely Dobutamine Hydrochloride in 5% Dextrose dobutamine hydrochloride PDR
Max dose for geriatric 28.8 mg/kg/day 20 mcg/kg/minute intravenous infusion, iv in drop Dobutamine Hydrochloride in 5% Dextrose dobutamine hydrochloride PDR
Max dose for geriatric 57.6 mg/kg/day 40 mcg/kg/minute intravenous infusion, iv in drop; rarely Dobutamine Hydrochloride in 5% Dextrose dobutamine hydrochloride PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1