Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00833 ...
Drug Name Cefaclor
Molecular Weight 367.807
Molecular Formula C15H14ClN3O4S
CAS Number 53994-73-3
SMILES [H][C@]12SCC(Cl)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=CC=C1)C(O)=O
External Links
DRUGBANK DB00833
PubChem Compound 51039
PDR 1541
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 0.4 - 0.4 - DRUGBANK
Melting Point 327.0 ℃ 327 ℃ DRUGBANK
Water Solubility 10000.0 mg/L 10000 mg/L YALKOWSKY,SH & DANNENFELSER,RM 1992)

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Metabolic 72.5 % 60-85 % Urinary excretion; DRUGBANK
Half-life 0.75 h 0.6-0.9 h DRUGBANK
Eliminate Route 72.5 % ~60-85 % Urinary excretion; DRUGBANK
Eliminate Route 72.5 % ~60-85 % Urinary excretion; Unchanged drug; DRUGBANK
Protein Binding 23.5 % 23.5 % DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for infants 40.0 mg/kg/day 40 mg/kg/day Liquid Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for children 40.0 mg/kg/day 40 mg/kg/day PO, oral Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for children 1000.0 mg/day 1 g/day intravenous injection, IV Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for adolescents 40.0 mg/kg/day 40 mg/kg/day PO, oral Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for adolescents 1000.0 mg/day 1 g/day PO, oral Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for adolescents 1000.0 mg/day 1 g/day PO, oral Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for adolescents 40.0 mg/kg/day 40 mg/kg/day PO, oral Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for adolescents 1000.0 mg/day 1 g/day PO, oral Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for adults 1500.0 mg/day 1.5 g/day Capsule, PO, Oral Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for adults 1500.0 mg/day 1.5 g/day Liquid Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for adults 1000.0 mg/day 1 g/day Tablet,PO，oral Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for geriatric 1500.0 mg/day 1.5 g/day Capsule, PO, Oral Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for geriatric 1500.0 mg/day 1.5 g/day Liquid Cefaclor Extended-Release Tablets cefaclor PDR
Max dose for geriatric 1000.0 mg/day 1 g/day Tablet,PO，oral Cefaclor Extended-Release Tablets cefaclor PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1