Basic Information
| Drug ID | DDPD00831 |
|
| Drug Name | Trifluoperazine | |
| Molecular Weight | 407.496 | |
| Molecular Formula | C21H24F3N3S | |
| CAS Number | 117-89-5 | |
| SMILES | CN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(C=C3)C(F)(F)F)CC1 | |
| External Links | ||
| DRUGBANK | DB00831 | |
| T3DB | T3D2905 | |
| PubChem Compound | 5566 | |
| PDR | 1985 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 5.03 | - | 5.03 | - | HANSCH,C ET AL. (1995) |
| Water Solubility | 12.2 | mg/L | 12.2 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| Log S | -4.52 | - | -4.52 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 15.0 | h | 10-20 | h | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 15.0 | mg/day | 15 | mg/day | PO, oral | Trifluoperazine Hydrochloride | trifluoperazine hydrochloride | PDR |
| Max dose for adolescents | 15.0 | mg/day | 15 | mg/day | PO, oral | Trifluoperazine Hydrochloride | trifluoperazine hydrochloride | PDR |
| Max dose for adolescents | 20.0 | mg/day | 20 | mg/day | PO, oral | Trifluoperazine Hydrochloride | trifluoperazine hydrochloride | PDR |
| Max dose for adults | 40.0 | mg/day | 40 | mg/day | PO, oral | Trifluoperazine Hydrochloride | trifluoperazine hydrochloride | PDR |
| Max dose for geriatric | 40.0 | mg/day | 40 | mg/day | PO, oral | Trifluoperazine Hydrochloride | trifluoperazine hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1