Basic Information
| Drug ID | DDPD00810 |
|
| Drug Name | Biperiden | |
| Molecular Weight | 311.4611 | |
| Molecular Formula | C21H29NO | |
| CAS Number | 514-65-8 | |
| SMILES | OC(CCN1CCCCC1)(C1CC2CC1C=C2)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00810 | |
| T3DB | T3D2897 | |
| PubChem Compound | 2381 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 4.25 | - | 4.25 | - | SANGSTER (1993) |
| Melting Point | 114.0 | ℃ | 114 | ℃ | PhysProp |
| Water Solubility | 25.1 | mg/L | 25.1 | mg/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 87.0 | % | 87 | % | DRUGBANK | |
| Clearance | 0.72 | L/h/kg | 12 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 12.0 | L/kg | 12 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 24.0 | h | 24 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 | 760.0 | mg/kg | 760.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 760.0 | mg/kg | 760.0 | mg/kg | PO, oral; Rattus, Rat; | T3DB |
| Protein Binding | 60.0 | % | 60 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1