Basic Information
| Drug ID | DDPD00804 |
|
| Drug Name | Dicyclomine | |
| Molecular Weight | 309.4867 | |
| Molecular Formula | C19H35NO2 | |
| CAS Number | 77-19-0 | |
| SMILES | CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1 | |
| External Links | ||
| DRUGBANK | DB00804 | |
| PubChem Compound | 3042 | |
| PDR | 1358 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 165.5 | ℃ | 165-166 | ℃ | Van Campen, M.G. Jr. and Tilford, C.H.; US.Patent 2,474,796; June 28, 1949; assigned to The Wm. S. Merrell Company. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 1.3 | h | 1-1.5 | h | DRUGBANK | |
| Volume of Distribution | 3.7 | L/kg | 3.65 | L/kg | intravenous injection, IV; | DRUGBANK |
| Half-life | 1.8 | h | ~1.8 | h | elimination half-life; | DRUGBANK |
| Toxicity LD50 | 625.0 | mg/kg | 625.0 | mg/kg | PO, oral; mouse; | DRUGBANK |
| Eliminate Route | 79.5 | % | 79.5 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 8.4 | % | 8.4 | % | Faeces excretion; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for infants | 20.0 | mg/day | 20 | mg/day | PO, oral | Bentyl | dicyclomine hydrochloride | PDR |
| Max dose for children | 40.0 | mg/day | 40 | mg/day | PO, oral | Bentyl | dicyclomine hydrochloride | PDR |
| Max dose for adolescents | 160.0 | mg/day | 160 | mg/day | PO, oral | Bentyl | dicyclomine hydrochloride | PDR |
| Max dose for adults | 160.0 | mg/day | 160 | mg/day | PO, oral | Bentyl | dicyclomine hydrochloride | PDR |
| Max dose for adults | 80.0 | mg/day | 80 | mg/day | IM,intramuscular injection | Bentyl | dicyclomine hydrochloride | PDR |
| Max dose for elderly | 160.0 | mg/day | 160 | mg/day | PO, oral | Bentyl | dicyclomine hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1