Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.0 | - | 2.0 | - | DRUGBANK |
| Water Solubility | 4000.0 | mg/L | 4000 | mg/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 2.5 | L/h/kg | 41.5 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.50 | L/kg | 0.5 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 0.0833 | h | ~5 | min | elimination half-life; mild hypertensives; mild hepatic impairment; Metabolite; | DRUGBANK | Half-life | 1.0 | h | 1 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route | 90.0 | % | ~90 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 10.0 | % | ~10 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 4.0 | % | 4 | % | Unchanged drug; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for infants | 1.152 | mg/kg/day | 0.8 | mcg/kg/min | intravenous infusion, iv in drop | Corlopam | fenoldopam mesylate | PDR |
| Max dose for children | 0.8 | mcg/kg/min | 0.8 | mcg/kg/min | intravenous infusion, iv in drop | Corlopam | fenoldopam mesylate | PDR |
| Max dose for adults | 2.304 | mg/kg/day | 1.6 | mcg/kg/min | intravenous infusion, iv in drop | Corlopam | fenoldopam mesylate | PDR |
| Max dose for elderly | 2.304 | mg/kg/day | 1.6 | mcg/kg/min | intravenous infusion, iv in drop | Corlopam | fenoldopam mesylate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1