Basic Information
| Drug ID | DDPD00790 |
|
| Drug Name | Perindopril | |
| Molecular Weight | 368.4678 | |
| Molecular Formula | C19H32N2O5 | |
| CAS Number | 82834-16-0 | |
| SMILES | [H][C@]12C[C@H](N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@@]1([H])CCCC2)C(O)=O | |
| External Links | ||
| DRUGBANK | DB00790 | |
| PubChem Compound | 107807 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.6 | - | 2.6 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Factor | Reference |
|---|---|---|---|---|---|---|---|
| Bioavailability | 70.0 | % | 65-75 | % | food; | food ↓ ; | DRUGBANK | Bioavailability | 20.0 | % | 20 | % | Active metabolite; | DRUGBANK |
| T Max | 1.0 | h | 1 | h | PO, oral; | DRUGBANK | |
| Metabolic | 6.5 | % | 1-12 | % | Urinary excretion; | DRUGBANK | |
| Clearance | 17.4 | L/h | 219-362 | ml/min | PO, oral; | DRUGBANK | |
| Half-life | 1.2 | h | 1.2 | h | DRUGBANK | Half-life | 75.0 | h | 30-120 | h | DRUGBANK |
| Eliminate Route | 8.0 | % | 4-12 | % | Urinary excretion; Unchanged drug; | DRUGBANK | |
| Protein Binding | 15.0 | % | 10-20 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1