DETAILS

Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID	DDPD00789
Drug Name	Gadopentetic acid
Molecular Weight	547.58
Molecular Formula	C14H20GdN3O10
CAS Number	80529-93-7
SMILES	[Gd+3].OC(=O)CN(CCN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O)CC([O-])=O
External Links
	DRUGBANK	DB00789
	PubChem Compound	55466
	PDR	1010
	Drugs.com	Drugs.com Drug Page

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Reference
Clearance	0.12	L/h/kg	1.94±0.28	ml/min/kg	normal,healthy;	DRUGBANK
Volume of Distribution	0.27	L/kg	266±43	mL/kg		DRUGBANK
Half-life	0.20	h	12	min	distribution half-life;	DRUGBANK
Half-life	1.7	h	100	min	elimination half-life;	DRUGBANK
Eliminate Route	83.0	%	83±14	%		DRUGBANK
Eliminate Route	91.0	%	91±13	%		DRUGBANK

Maximum Dosage

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Brand Name	Component	Reference
Max dose for children	0.2	ml/kg	0.2	ml/kg	intravenous injection, IV	Magnevist Injection	gadopentetate dimeglumine	PDR
Max dose for children	0.1	mmol/kg	0.1	mmol/kg	intravenous injection, IV	Magnevist Injection	gadopentetate dimeglumine	PDR
Max dose for adolescents	0.2	ml/kg	0.2	mL/kg	intravenous injection, IV	Magnevist Injection	gadopentetate dimeglumine	PDR
Max dose for adolescents	0.1	mmol/kg	0.1	mmol/kg	intravenous injection, IV	Magnevist Injection	gadopentetate dimeglumine	PDR
Max dose for adults	0.2	ml/kg	0.2	ml/kg	intravenous injection, IV	Magnevist Injection	gadopentetate dimeglumine	PDR
Max dose for adults	0.1	mmoL/kg	0.1	mmoL/kg	intravenous injection, IV	Magnevist Injection	gadopentetate dimeglumine	PDR
Max dose for geriatric	0.2	ml/kg	0.2	ml/kg	intravenous injection, IV	Magnevist Injection	gadopentetate dimeglumine	PDR
Max dose for geriatric	0.1	mmol/kg	0.1	mmol/kg	intravenous injection, IV	Magnevist Injection	gadopentetate dimeglumine	PDR

Drug Property Radar Chart

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1