Basic Information
| Drug ID | DDPD00780 |
|
| Drug Name | Phenelzine | |
| Molecular Weight | 136.1943 | |
| Molecular Formula | C8H12N2 | |
| CAS Number | 51-71-8 | |
| SMILES | NNCCC1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00780 | |
| T3DB | T3D2889 | |
| PubChem Compound | 3675 | |
| PDR | 462 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Boiling Point | 74.0 | ℃ | 74 | ℃ | US Environmental Protection Agency (liquid form) |
| Melting Point | 159.0 | ℃ | 157-161 | ℃ | 'MSDS' for phenelzine sulfate (solid form) |
| Water Solubility | 29100.0 | mg/L | 29.1 | g/L | MSDS' for phenelzine sulfate solid form) |
| pKa | 7.25 | - | 6.5-8 | - | Zaragoza F. Lead Optimization for Medicinal Chemists. (2012) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| C Max | 19.8 | ng/ml | 19.8 | ng/ml | PO, oral; | DRUGBANK |
| T Max | 0.72 | h | 43 | min | PO, oral; | DRUGBANK |
| Half-life | 11.6 | h | 11.6 | h | human, homo sapiens; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 90.0 | mg/day | 90 | mg/day | PO, oral | Nardil | phenelzine sulfate | PDR |
| Max dose for geriatric | 90.0 | mg/day | 90 | mg/day | PO, oral | Nardil | phenelzine sulfate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1