Basic Information
| Drug ID | DDPD00772 |
|
| Drug Name | Malathion | |
| Molecular Weight | 330.358 | |
| Molecular Formula | C10H19O6PS2 | |
| CAS Number | 121-75-5 | |
| SMILES | CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC | |
| External Links | ||
| DRUGBANK | DB00772 | |
| T3DB | T3D3870 | |
| ATSDR | ATSDR Page | |
| PubChem Compound | 4004 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.36 | - | 2.36 | - | HANSCH,C ET AL. (1995) |
| Boiling Point | 156.5 | ℃ | 156-157 | ℃ | PhysProp |
| Melting Point | 2.8 | ℃ | 2.8 | ℃ | PhysProp |
| Water Solubility | 143.0 | mg/L | 143 | mg/L | BOWMAN,BT & SANS,WW 1983) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Factor | Reference |
|---|---|---|---|---|---|---|---|
| Absorption | 8.0 | % | 8 | % | skin/dermal; skin disease; | skin disease ↑ ; | DRUGBANK |
| Half-life | 16.0 | h | 8-24 | h | DRUGBANK | ||
| Toxicity LD50 | 5500.0 | mg/kg | 1000->10000 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 4000.0 | mg/kg | >4000 | mg/kg | skin/dermal; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 5500.0 | mg/kg | 1000-10000 | mg/kg | PO, oral; Rattus, Rat; | T3DB | Toxicity LD50 | 4000.0 | mg/kg | >4000 | mg/kg | skin/dermal; Rattus, Rat; | T3DB |
| Toxicity MRLs | 0.000200 | mg/L | 0.2 | mg/m3 | inhalation, IH; | ATSDR | Toxicity MRLs | 0.000020 | mg/L | 0.02 | mg/m3 | inhalation, IH; | ATSDR | Toxicity MRLs | 0.0200 | mg/kg/day | 0.02 | mg/kg/day | PO, oral; | ATSDR | Toxicity MRLs | 0.0200 | mg/kg/day | 0.02 | mg/kg/day | PO, oral; Oral multiple dose; | ATSDR |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1