Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00746 ...
Drug Name Deferoxamine
Molecular Weight 560.684
Molecular Formula C25H48N6O8
CAS Number 70-51-9
SMILES CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN
External Links
DRUGBANK DB00746
PubChem Compound 2973
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P -2.2 - -2.2 - DRUGBANK
Melting Point 140.0 ℃ 140 ℃ PhysProp
Water Solubility 12000.0 mg/L 12000 mg/L MERCK INDEX 1996)

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Half-life 1.0 h 1 h elimination half-life; normal,healthy; DRUGBANK
Half-life 6.0 h 6 h terminal half-life; normal,healthy; DRUGBANK
Toxicity LD50 340.0 mg/kg 340.0 mg/kg intravenous injection, IV; mouse; DRUGBANK
Toxicity LD50 520.0 mg/kg 520.0 mg/kg intravenous injection, IV; Rattus, Rat; DRUGBANK
Toxicity LD50 600.0 mg/kg 600.0 mg/kg intravenous injection, IV; rabbit; DRUGBANK
Toxicity LD50 1600.0 mg/kg 1600.0 mg/kg subcutaneous injection, SC; mouse; DRUGBANK
Toxicity LD50 1000.0 mg/kg >1000 mg/kg subcutaneous injection, SC; Rattus, Rat; DRUGBANK
Toxicity LD50 3000.0 mg/kg >3000 mg/kg PO, oral; mouse; DRUGBANK
Toxicity LD50 1000.0 mg/kg >1000 mg/kg PO, oral; Rattus, Rat; DRUGBANK
Protein Binding 10.0 % <10 % high protein binding; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1