Basic Information
| Drug ID | DDPD00745 |
|
| Drug Name | Modafinil | |
| Molecular Weight | 273.35 | |
| Molecular Formula | C15H15NO2S | |
| CAS Number | 68693-11-8 | |
| SMILES | NC(=O)CS(=O)C(C1=CC=CC=C1)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00745 | |
| T3DB | T3D2876 | |
| PubChem Compound | 4236 | |
| PDR | 2332 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.6 | - | 0.6 | - | DRUGBANK |
| Melting Point | 165.0 | ℃ | 164-166 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Volume of Distribution | 0.90 | L/kg | 0.9 | L/kg | DRUGBANK | |
| Half-life | 119.0 | h | 23-215 | h | DRUGBANK | |
| Protein Binding | 60.0 | % | 60 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adolescents | 400.0 | mg/day | 400 | mg/day | PO, oral | Provigil | modafinil | PDR |
| Max dose for adults | 400.0 | mg/day | 400 | mg/day | PO, oral | Provigil | modafinil | PDR |
| Max dose for geriatric | 400.0 | mg/day | 400 | mg/day | PO, oral | Provigil | modafinil | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1