Basic Information
| Drug ID | DDPD00733 |
|
| Drug Name | Pralidoxime | |
| Molecular Weight | 137.1592 | |
| Molecular Formula | C7H9N2O | |
| CAS Number | 6735-59-7 | |
| SMILES | C[N+]1=C(\C=N\O)C=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00733 | |
| PubChem Compound | 5353894 | |
| PDR | 1131 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.564 | - | 1.564 | - | DRUGBANK |
| Melting Point | 220.0 | ℃ | 215-225 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.54 | L/h/kg | 9 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.80 | L/kg | 0.8 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 1.3 | h | 74-77 | min | DRUGBANK | Half-life | 1.4 | h | 1.4 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 50.0 | mg/kg/dose | 50 | mg/kg/dose | intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; | Protopam Chloride | pralidoxime chloride | PDR |
| Max dose for children | 2000.0 | mg/dose | 2 | g/dose | intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; | Protopam Chloride | pralidoxime chloride | PDR |
| Max dose for adolescents | 50.0 | mg/kg/dose | 50 | mg/kg/dose | intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; | Protopam Chloride | pralidoxime chloride | PDR |
| Max dose for adolescents | 2000.0 | mg/dose | 2 | g/dose | intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; | Protopam Chloride | pralidoxime chloride | PDR |
| Max dose for adults | 2000.0 | mg/dose | 2 | g/dose | intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; | Protopam Chloride | pralidoxime chloride | PDR |
| Max dose for elderly | 2.0 | g/dose | 2 | g/dose | intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; | Protopam Chloride | pralidoxime chloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1