Basic Information
| Drug ID | DDPD00730 |
|
| Drug Name | Thiabendazole | |
| Molecular Weight | 201.248 | |
| Molecular Formula | C10H7N3S | |
| CAS Number | 148-79-8 | |
| SMILES | N1C2=CC=CC=C2N=C1C1=CSC=N1 | |
| External Links | ||
| DRUGBANK | DB00730 | |
| T3DB | T3D3931 | |
| PubChem Compound | 5430 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.47 | - | 2.47 | - | NIELSEN,LS ET AL. (1992) |
| Melting Point | 300.0 | ℃ | 300 | ℃ | PhysProp |
| Water Solubility | 50.0 | mg/L | 50 | mg/L | WAUCHOPE,RD ET AL. 1991A) |
| pKa | 4.64 | - | 4.64 | - | CHAMBERLAIN,K ET AL. (1996) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 1.5 | h | 1-2 | h | PO, oral; | DRUGBANK |
| Metabolic | 100.0 | % | ~100 | % | Liver metabolism; | DRUGBANK |
| Half-life | 1.2 | h | 1.2(0.9-2) | h | normal,healthy; | DRUGBANK | Half-life | 1.2 | h | 1.2(0.9-2) | h | anephric; | DRUGBANK | Half-life | 1.7 | h | 1.7(1.4-2) | h | normal,healthy; | DRUGBANK | Half-life | 1.7 | h | 1.7(1.4-2) | h | anephric; | DRUGBANK |
| Toxicity LD50 | 3600.0 | mg/kg | 3.6 | g/kg | PO, oral; mouse; | DRUGBANK | Toxicity LD50 | 3100.0 | mg/kg | 3.1 | g/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 3800.0 | mg/kg | 3.8 | g/kg | PO, oral; rabbit; | DRUGBANK | Toxicity LD50 | 3600.0 | mg/kg | 3.6 | g/kg | PO, oral; mouse; | T3DB | Toxicity LD50 | 3100.0 | mg/kg | 3.1 | g/kg | PO, oral; Rattus, Rat; | T3DB | Toxicity LD50 | 3800.0 | mg/kg | 3.8 | g/kg | PO, oral; rabbit; | T3DB |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1