Basic Information
| Drug ID | DDPD00721 |
|
| Drug Name | Procaine | |
| Molecular Weight | 236.3101 | |
| Molecular Formula | C13H20N2O2 | |
| CAS Number | 59-46-1 | |
| SMILES | CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 | |
| External Links | ||
| DRUGBANK | DB00721 | |
| T3DB | T3D2869 | |
| PubChem Compound | 4914 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.14 | - | 2.14 | - | AVDEEF,A (1997) |
| Melting Point | 61.0 | ℃ | 61 | ℃ | PhysProp |
| Water Solubility | 9450.0 | mg/L | 9450 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| pKa | 8.05 | - | 8.05 | - | PERRIN,DD (1965) |
| Log S | -1.4 | - | -1.4 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Factor | Reference |
|---|---|---|---|---|---|---|---|
| Bioavailability | 25.0 | % | 25(6-60) | % | PO, oral; food; | food → ; | DRUGBANK |
| C Max | 58.0 | ng/ml | 58.0 | ng/ml | PO, oral; food; | food → ; | DRUGBANK |
| T Max | 7.0 | h | 6-8 | h | PO, oral; food; | food → ; | DRUGBANK |
| Half-life | 0.13 | h | 7.7 | min | DRUGBANK | ||
| Toxicity LD50 | 350.0 | mg/kg | 350.0 | mg/kg | PO, oral; mouse; | T3DB |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1