Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00713 ...
Drug Name Oxacillin
Molecular Weight 401.436
Molecular Formula C19H19N3O5S
CAS Number 66-79-5
SMILES [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C1=C(C)ON=C1C1=CC=CC=C1)C(O)=O
External Links
DRUGBANK DB00713
PubChem Compound 6196
PDR 3066
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 2.38 - 2.38 - HANSCH,C ET AL. (1995)
Melting Point 188.0 ℃ 188 ℃ PhysProp
Water Solubility 13.9 mg/L 13.9 mg/L DRUGBANK
pKa 2.72 - 2.72 - SANGSTER (1994)

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.38 L/h/kg 6.3 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.19 L/kg 0.19 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 0.42 h 20-30 min DRUGBANK
Half-life 0.70 h 0.7 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Protein Binding 94.2 % 94.2±2.1 % DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for neonates 25.0 mg/kg/day 25 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for neonates 200.0 mg/kg/day 200 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for neonates 150.0 mg/kg/day 150 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for neonates 150.0 mg/kg/day 150 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for neonates 100.0 mg/kg/day 100 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for infants 100.0 mg/kg/day 100 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for infants 200.0 mg/kg/day 200 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for children 6000.0 mg/day 6 g/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for children 200.0 mg/kg/day 200 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for children 100.0 mg/kg/day 100 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for children 200.0 mg/kg/day 200 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for children 12000.0 mg/day 12 g/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for adolescents 6000.0 mg/day 6 g/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for adolescents 200.0 mg/kg/day 200 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for adolescents 100.0 mg/kg/day 100 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for adolescents 200.0 mg/kg/day 200 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for adolescents 12000.0 mg/day 12 g/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for adults 6000.0 mg/day 6 g/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for adults 12000.0 mg/day 12 g/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for geriatric 6000.0 mg/day 6 g/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR
Max dose for geriatric 12000.0 mg/day 12 g/day intravenous injection, IV;IM,intramuscular injection; Oxacillin oxacillin PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1