Basic Information
| Drug ID | DDPD00707 |
|
| Drug Name | Porfimer sodium | |
| Molecular Weight | N.A. | |
| Molecular Formula | N.A. | |
| CAS Number | 87806-31-3 | |
| SMILES | CCC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C(=C(C(=N5)C=C1N2)C)C(C)O)C)CCC(=O)O)C(=C3C)CCC(=O)O)C.[Na+] | |
| External Links | ||
| DRUGBANK | DB00707 | |
| PubChem Compound | 137321858 | |
| PDR | 2755 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.8 | - | 2.8 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 12.0 | L/h | 199.7±56.9 | ml/min | Oral single dose; normal,healthy; | DRUGBANK |
| Volume of Distribution | 0.49 | L/kg | 0.49±0.28 | L/kg | tumor; patients; Male, men; | DRUGBANK |
| Half-life | 231.0 | h | 10-452 | h | DRUGBANK | |
| Protein Binding | 90.0 | % | ~90 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 2.0 | mg/kg | 2 | mg/kg | intravenous injection, IV | Photofrin | porfimer sodium | PDR |
| Max dose for elderly | 2.0 | mg/kg | 2 | mg/kg | intravenous injection, IV | Photofrin | porfimer sodium | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1