Basic Information
| Drug ID | DDPD00703 |
|
| Drug Name | Methazolamide | |
| Molecular Weight | 236.26 | |
| Molecular Formula | C5H8N4O3S2 | |
| CAS Number | 554-57-4 | |
| SMILES | CN1N=C(SC1=NC(C)=O)S(N)(=O)=O | |
| External Links | ||
| DRUGBANK | DB00703 | |
| PubChem Compound | 4100 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.13 | - | 0.13 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 213.5 | ℃ | 213.5 | ℃ | PhysProp |
| Water Solubility | 3500.0 | mg/L | 3500 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| pKa | 7.3 | - | 7.3 | - | DRUGBANK |
| Log S | -1.83 | - | -1.83 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Volume of Distribution | 20.0 | L | 17-23 | L | DRUGBANK | |
| Half-life | 14.0 | h | 14 | h | DRUGBANK | |
| Protein Binding | 55.0 | % | 55 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1