Basic Information
| Drug ID | DDPD00690 |
|
| Drug Name | Flurazepam | |
| Molecular Weight | 387.878 | |
| Molecular Formula | C21H23ClFN3O | |
| CAS Number | 17617-23-1 | |
| SMILES | CCN(CC)CCN1C2=C(C=C(Cl)C=C2)C(=NCC1=O)C1=CC=CC=C1F | |
| External Links | ||
| DRUGBANK | DB00690 | |
| T3DB | T3D2860 | |
| PubChem Compound | 3393 | |
| PDR | 1969 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.8 | - | 3.8 | - | DRUGBANK |
| Melting Point | 205.0 | ℃ | 190-220 | ℃ | British Patent 1,040,548. |
| Water Solubility | 500000.0 | mg/L | 500 | mg/ml | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 2.3 | h | 2.3 | h | DRUGBANK | Half-life | 73.5 | h | 47-100 | h | elimination half-life; | DRUGBANK |
| Protein Binding | 83.0 | % | 83 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Frequency | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Max dose for adolescents | 30.0 | mg/day | 30 | mg/day | PO, oral; hs | Flurazepam Hydrochloride | flurazepam hydrochloride | PDR | |
| Max dose for adults | 30.0 | mg/day | 30 | mg/day | PO, oral; hs | Flurazepam Hydrochloride | flurazepam hydrochloride | PDR | |
| Max dose for elderly | 15.0 | mg/day | 15 | mg/day | PO, oral | hs | Flurazepam Hydrochloride | flurazepam hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1