Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00668 ...
Drug Name Epinephrine
Molecular Weight 183.2044
Molecular Formula C9H13NO3
CAS Number 51-43-4
SMILES CNC[C@H](O)C1=CC(O)=C(O)C=C1
External Links
DRUGBANK DB00668
PubChem Compound 5816
PDR 1233
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Caco-2 Permeability -6.02 - -6.02 - https://pubchem.ncbi.nlm.nih.gov/compound/epinephrine#section=Stability
Log P -1.37 - -1.37 - https://pubchem.ncbi.nlm.nih.gov/compound/epinephrine#section=Vapor-Pressure
Boiling Point 215.0 ℃ 215 ℃ MSDS
Melting Point 211.5 ℃ 211.5 ℃ https://pubchem.ncbi.nlm.nih.gov/compound/epinephrine
Water Solubility 100.0 mg/L <0.1 mg/ml https://pubchem.ncbi.nlm.nih.gov/compound/epinephrine#section=Melting-Point
pKa 8.59 - 8.59 - https://pubchem.ncbi.nlm.nih.gov/compound/epinephrine#section=Stability

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Half-life 0.0417 h ~2-3 min elimination half-life; DRUGBANK
Toxicity LD50 62.0 mg/kg 62.0 mg/kg skin/dermal; Rattus, Rat; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for neonates 0.03 mg/kg/dose 0.03 mg/kg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for neonates 0.1 mg/kg/dose 0.1 mg/kg/dose ET Adrenaclick epinephrine PDR
Max dose for infants 0.01 mg/kg/dose 0.01 mg/kg/dose intravenous injection, IV;IO; Adrenaclick epinephrine PDR
Max dose for infants 1.0 mg/dose 1 mg/dose intravenous injection, IV;IO; Adrenaclick epinephrine PDR
Max dose for infants 0.1 mg/kg/dose 0.1 mg/kg/dose EI Adrenaclick epinephrine PDR
Max dose for infants 2.5 mg/dose 2.5 mg/dose EI Adrenaclick epinephrine PDR
Max dose for infants 0.01 mg/kg/dose 0.01 mg/kg/dose Adrenaclick epinephrine PDR
Max dose for infants 0.5 mg/dose 0.5 mg/dose IM,intramuscular injection;subcutaneous injection, SC; Adrenaclick epinephrine PDR
Max dose for infants 1.0 mg/dose 1 mg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for infants 0.5 ml/dose 0.5 ml/dose Adrenaclick epinephrine PDR
Max dose for infants 0.01 mg/kg/dose 0.01 mg/kg/dose subcutaneous injection, SC Adrenaclick epinephrine PDR
Max dose for infants 0.5 mg/dose 0.5 mg/dose subcutaneous injection, SC Adrenaclick epinephrine PDR
Max dose for children 0.01 mg/kg/dose 0.01 mg/kg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for children 1.0 mg/dose 1 mg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for children 0.1 mg/kg/dose 0.1 mg/kg/dose EI Adrenaclick epinephrine PDR
Max dose for children 2.5 mg/dose 2.5 mg/dose EI Adrenaclick epinephrine PDR
Max dose for children 0.01 mg/kg/dose 0.01 mg/kg/dose Adrenaclick epinephrine PDR
Max dose for children 0.5 mg/dose 0.5 mg/dose IM,intramuscular injection;subcutaneous injection, SC; Adrenaclick epinephrine PDR
Max dose for children 1.0 mg/dose 1 mg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for children 0.5 ml/dose 0.5 ml/dose Adrenaclick epinephrine PDR
Max dose for children 0.01 mg/kg/dose 0.01 mg/kg/dose subcutaneous injection, SC Adrenaclick epinephrine PDR
Max dose for children 0.5 mg/dose 0.5 mg/dose subcutaneous injection, SC Adrenaclick epinephrine PDR
Max dose for children 8.0 oral inhalations/day 8 oral inhalations/day inhalation, IH Adrenaclick epinephrine PDR
Max dose for children 0.01 mg/kg/dose 0.01 mg/kg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for children 1.0 mg/dose 1 mg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for children 0.1 mg/kg/dose 0.1 mg/kg/dose EI Adrenaclick epinephrine PDR
Max dose for children 2.5 mg/dose 2.5 mg/dose EI Adrenaclick epinephrine PDR
Max dose for children 0.01 mg/kg/dose 0.01 mg/kg/dose Adrenaclick epinephrine PDR
Max dose for children 0.5 mg/dose 0.5 mg/dose IM,intramuscular injection;subcutaneous injection, SC; Adrenaclick epinephrine PDR
Max dose for children 1.0 mg/dose 1 mg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for children 0.5 ml/dose 0.5 ml/dose Adrenaclick epinephrine PDR
Max dose for children 0.01 mg/kg/dose 0.01 mg/kg/dose subcutaneous injection, SC Adrenaclick epinephrine PDR
Max dose for children 0.5 mg/dose 0.5 mg/dose subcutaneous injection, SC Adrenaclick epinephrine PDR
Max dose for children 0.01 mg/kg/dose 0.01 mg/kg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for children 1.0 mg/dose 1 mg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for children 0.1 mg/kg/dose 0.1 mg/kg/dose EI Adrenaclick epinephrine PDR
Max dose for children 2.5 mg/dose 2.5 mg/dose EI Adrenaclick epinephrine PDR
Max dose for children 0.01 mg/kg/dose 0.01 mg/kg/dose Adrenaclick epinephrine PDR
Max dose for children 0.5 mg/dose 0.5 mg/dose IM,intramuscular injection;subcutaneous injection, SC; Adrenaclick epinephrine PDR
Max dose for children 1.0 mg/dose 1 mg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for children 0.5 ml/dose 0.5 ml/dose Adrenaclick epinephrine PDR
Max dose for children 0.01 mg/kg/dose 0.01 mg/kg/dose subcutaneous injection, SC Adrenaclick epinephrine PDR
Max dose for children 0.5 mg/dose 0.5 mg/dose subcutaneous injection, SC Adrenaclick epinephrine PDR
Max dose for adolescents 0.01 mg/kg/dose 0.01 mg/kg/dose intravenous injection, IV;IO; Adrenaclick epinephrine PDR
Max dose for adolescents 1.0 mg/dose 1 mg/dose intravenous injection, IV;IO; Adrenaclick epinephrine PDR
Max dose for adolescents 0.1 mg/kg/dose 0.1 mg/kg/dose EI Adrenaclick epinephrine PDR
Max dose for adolescents 2.5 mg/dose 2.5 mg/dose EI Adrenaclick epinephrine PDR
Max dose for adolescents 0.01 mg/kg/dose 0.01 mg/kg/dose Adrenaclick epinephrine PDR
Max dose for adolescents 0.5 mg/dose 0.5 mg/dose IM,intramuscular injection;subcutaneous injection, SC; Adrenaclick epinephrine PDR
Max dose for adolescents 1.0 mg/dose 1 mg/dose intravenous injection, IV Adrenaclick epinephrine PDR
Max dose for adolescents 0.01 mg/kg/dose 0.01 mg/kg/dose subcutaneous injection, SC Adrenaclick epinephrine PDR
Max dose for adolescents 0.5 mg/dose 0.5 mg/dose subcutaneous injection, SC Adrenaclick epinephrine PDR
Max dose for adolescents 8.0 oral inhalations/day 8 oral inhalations/day inhalation, IH Adrenaclick epinephrine PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1