Basic Information
| Drug ID | DDPD00665 |
|
| Drug Name | Nilutamide | |
| Molecular Weight | 317.2207 | |
| Molecular Formula | C12H10F3N3O4 | |
| CAS Number | 63612-50-0 | |
| SMILES | CC1(C)NC(=O)N(C1=O)C1=CC(=C(C=C1)[N+]([O-])=O)C(F)(F)F | |
| External Links | ||
| DRUGBANK | DB00665 | |
| T3DB | T3D4783 | |
| PubChem Compound | 4493 | |
| PDR | 1681 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.8 | - | 1.8 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 100.0 | % | 100 | % | DRUGBANK | |
| Metabolic | 2.0 | % | <2 | % | Urinary excretion; | DRUGBANK |
| Half-life | 48.6 | h | 38.0-59.1 | h | DRUGBANK | |
| Eliminate Route | 2.0 | % | <2 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 300.0 | mg/day | 300 | mg/day | PO, oral | Nilandron | nilutamide | PDR |
| Max dose for elderly | 300.0 | mg/day | 300 | mg/day | PO, oral | Nilandron | nilutamide | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1