Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00652 ...
Drug Name Pentazocine
Molecular Weight 285.4238
Molecular Formula C19H27NO
CAS Number 359-83-1
SMILES C[C@H]1[C@H]2CC3=CC=C(O)C=C3[C@]1(C)CCN2CC=C(C)C
External Links
DRUGBANK DB00652
T3DB T3D2850
PubChem Compound 441278
PDR 3002
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 4.64 - 4.64 - DAYLIGHT (1999)
Melting Point 146.3 ℃ 146.3 ℃ PhysProp
pKa 8.88 - 8.88 - SANGSTER (1994)

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 1.4 L/h/kg 23 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 3.4 L/kg 3.4 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 2.5 h 2-3 h DRUGBANK
Half-life 2.5 h 2.5 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for children 0.5 mg/kg 0.5 mg/kg IM,intramuscular injection Talwin pentazocine PDR
Max dose for children 30.0 mg 30 mg IM,intramuscular injection Talwin pentazocine PDR
Max dose for adolescents 360.0 mg/day 360 mg/day intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; Talwin pentazocine PDR
Max dose for adolescents 30.0 mg/dose 30 mg/dose intravenous injection, IV Talwin pentazocine PDR
Max dose for adolescents 60.0 mg/dose 60 mg/dose IM,intramuscular injection;subcutaneous injection, SC; Talwin pentazocine PDR
Max dose for adolescents 0.5 mg/kg 0.5 mg/kg IM,intramuscular injection Talwin pentazocine PDR
Max dose for adolescents 30.0 mg 30 mg IM,intramuscular injection Talwin pentazocine PDR
Max dose for adults 360.0 mg/day 360 mg/day intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; Talwin pentazocine PDR
Max dose for adults 30.0 mg/dose 30 mg/dose intravenous injection, IV Talwin pentazocine PDR
Max dose for adults 60.0 mg/dose 60 mg/dose IM,intramuscular injection;subcutaneous injection, SC; Talwin pentazocine PDR
Max dose for geriatric 360.0 mg/day 360 mg/day intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; Talwin pentazocine PDR
Max dose for geriatric 30.0 mg/dose 30 mg/dose intravenous injection, IV Talwin pentazocine PDR
Max dose for geriatric 60.0 mg/dose 60 mg/dose IM,intramuscular injection;subcutaneous injection, SC; Talwin pentazocine PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1