Basic Information
| Drug ID | DDPD00651 |
|
| Drug Name | Dyphylline | |
| Molecular Weight | 254.2426 | |
| Molecular Formula | C10H14N4O4 | |
| CAS Number | 479-18-5 | |
| SMILES | CN1C2=C(N(CC(O)CO)C=N2)C(=O)N(C)C1=O | |
| External Links | ||
| DRUGBANK | DB00651 | |
| PubChem Compound | 3182 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -1.9 | - | -1.9 | - | DRUGBANK |
| Melting Point | 156.0 | ℃ | 155-157 | ℃ | Jones, J.W. and Maney, P.V.; U.S. Patent 2,575,344; November 20,1951; assigned to the State of Iowa. |
| Water Solubility | 333000.0 | mg/L | 333000 | mg/L | MERCK INDEX 1996) |
| Log S | -0.17 | - | -0.17 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 2.0 | h | 2(1.8-2.1) | h | DRUGBANK | |
| Toxicity LD50 | 1954.0 | mg/kg | 1954.0 | mg/kg | PO, oral; mouse; | DRUGBANK |
| Eliminate Route | 88.0 | % | ~88 | % | Urinary excretion; Oral single dose; Unchanged drug; | DRUGBANK |
| Protein Binding | 84.0 | % | 84 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1