Basic Information
| Drug ID | DDPD00647 |
|
| Drug Name | Dextropropoxyphene | |
| Molecular Weight | 339.4712 | |
| Molecular Formula | C22H29NO2 | |
| CAS Number | 469-62-5 | |
| SMILES | CCC(=O)O[C@@](CC1=CC=CC=C1)([C@H](C)CN(C)C)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00647 | |
| T3DB | T3D2848 | |
| PubChem Compound | 10100 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 4.18 | - | 4.18 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 75.5 | ℃ | 75.5 | ℃ | PhysProp |
| Water Solubility | 3.32 | mg/L | 3.32 | mg/L | MCFARLAND,JW ET AL. 2001) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.16 | L/h | 2.6 | ml/min | DRUGBANK | |
| Volume of Distribution | 16.0 | L/kg | 16.0 | L/kg | DRUGBANK | |
| Half-life | 9.0 | h | 6-12 | h | DRUGBANK | |
| Toxicity LD50 | 230.0 | mg/kg | 230.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 230.0 | mg/kg | 230.0 | mg/kg | PO, oral; Rattus, Rat; | T3DB |
| Eliminate Route | 22.5 | % | ~20-25 | % | Urinary excretion; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1