Basic Information
| Drug ID | DDPD00646 |
|
| Drug Name | Nystatin | |
| Molecular Weight | 926.107 | |
| Molecular Formula | C47H75NO17 | |
| CAS Number | 1400-61-9 | |
| SMILES | C[C@H]1O[C@H](OC2CC3O[C@@](O)(CC(O)C3C(O)=O)CC(O)C(O)CCC(O)CC(O)CC(O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\CC\C=C\C=C\C=C\C=C\2)[C@@H](O)[C@@H](N)[C@@H]1O | |
| External Links | ||
| DRUGBANK | DB00646 | |
| T3DB | T3D2847 | |
| PubChem Compound | 11953884 | |
| PDR | 1531 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.5 | - | 0.5 | - | DRUGBANK |
| Melting Point | 160.0 | ℃ | 160 | ℃ | MSDS |
| Water Solubility | 360.0 | mg/L | 360 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Metabolic | 0 | % | ~0 | % | DRUGBANK | |
| Toxicity LD50 | 10000.0 | mg/kg | 10.0 | g/kg | PO, oral; Rattus, Rat; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for neonates | 800000.0 | units/day | 800000 | units/day | PO, oral | Nystatin Tablets | nystatin | PDR |
| Max dose for neonates | 400000.0 | units/day | 400000 | units/day | PO, oral | Nystatin Tablets | nystatin | PDR |
| Max dose for infants | 800000.0 | units/day | 800000 | units/day | PO, oral | Nystatin Tablets | nystatin | PDR |
| Max dose for children | 2400000.0 | units/day | 2400000 | units/day | PO, oral | Nystatin Tablets | nystatin | PDR |
| Max dose for adolescents | 2400000.0 | units/day | 2400000 | units/day | PO, oral | Nystatin Tablets | nystatin | PDR |
| Max dose for adults | 2400000.0 | units/day | 2400000 | units/day | PO, oral | Nystatin Tablets | nystatin | PDR |
| Max dose for adults | 100000.0 | units/day | 100000 | units/day | Vaginal Administration | Nystatin Tablets | nystatin | PDR |
| Max dose for geriatric | 2400000.0 | units/day | 2400000 | units/day | PO, oral | Nystatin Tablets | nystatin | PDR |
| Max dose for geriatric | 100000.0 | units/day | 100000 | units/day | Vaginal Administration | Nystatin Tablets | nystatin | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1