Basic Information
| Drug ID | DDPD00629 |
|
| Drug Name | Guanabenz | |
| Molecular Weight | 231.082 | |
| Molecular Formula | C8H8Cl2N4 | |
| CAS Number | 5051-62-7 | |
| SMILES | NC(N)=NN=CC1=C(Cl)C=CC=C1Cl | |
| External Links | ||
| DRUGBANK | DB00629 | |
| PubChem Compound | 3517 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Caco-2 Permeability | -4.5 | - | -4.5 | - | ADME Research, USCD |
| Log P | 3.2 | - | 3.2 | - | DRUGBANK |
| Melting Point | 226.0 | ℃ | 225-227 | ℃ | British Patent 1,019,120. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 75.0 | % | 75 | % | PO, oral; | DRUGBANK |
| Half-life | 6.0 | h | 6 | h | DRUGBANK | |
| Protein Binding | 90.0 | % | 90 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1