Basic Information
| Drug ID | DDPD00626 |
|
| Drug Name | Bacitracin | |
| Molecular Weight | 1422.693 | |
| Molecular Formula | C66H103N17O16S | |
| CAS Number | 1405-87-4 | |
| SMILES | CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CC2=CNC=N2)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC1=O)[C@@H](C)CC | |
| External Links | ||
| DRUGBANK | DB00626 | |
| PubChem Compound | 10909430 | |
| PDR | 2460 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 100.0 | % | 100 | % | IM,intramuscular injection; | DRUGBANK |
| Clearance | 11.6 | L/h | 105-283 | ml/min | Renal clearance; | DRUGBANK | Clearance | 9.5 | L/h | 159.0 | ml/min | Renal clearance; | DRUGBANK |
| Toxicity LD50 | 2000.0 | mg/kg | >2000 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
| Eliminate Route | 87.0 | % | 87 | % | Urinary excretion; IM,intramuscular injection; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for infants | 1000.0 | units/kg/day | 1000 | units/kg/day | IM,intramuscular injection | Bacitracin Injection | bacitracin | PDR |
| Max dose for infants | 900.0 | units/kg/day | 900 | units/kg/day | IM,intramuscular injection | Bacitracin Injection | bacitracin | PDR |
| Max dose for children | 1200.0 | units/kg/day | 1200 | units/kg/day | IM,intramuscular injection | Bacitracin Injection | bacitracin | PDR |
| Max dose for adolescents | 1200.0 | units/kg/day | 1200 | units/kg/day | IM,intramuscular injection | Bacitracin Injection | bacitracin | PDR |
| Max dose for adolescents | 0.0 | 0 | IM,intramuscular injection | Bacitracin Injection | bacitracin | PDR | ||
| Max dose for adults | 100000.0 | units/day | 100000 | units/day | IM,intramuscular injection | Bacitracin Injection | bacitracin | PDR |
| Max dose for adults | 25000.0 | units/dose | 25000 | units/dose | IM,intramuscular injection | Bacitracin Injection | bacitracin | PDR |
| Max dose for geriatric | 100000.0 | units/day | 100000 | units/day | IM,intramuscular injection | Bacitracin Injection | bacitracin | PDR |
| Max dose for geriatric | 25000.0 | units/dose | 25000 | units/dose | IM,intramuscular injection | Bacitracin Injection | bacitracin | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1