Basic Information
| Drug ID | DDPD00609 |
|
| Drug Name | Ethionamide | |
| Molecular Weight | 166.243 | |
| Molecular Formula | C8H10N2S | |
| CAS Number | 536-33-4 | |
| SMILES | CCC1=NC=CC(=C1)C(N)=S | |
| External Links | ||
| DRUGBANK | DB00609 | |
| PubChem Compound | 2761171 | |
| PDR | 1952 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.5 | - | 0.5 | - | DRUGBANK |
| Melting Point | 166.0 | ℃ | 166 | ℃ | Chimie et Atomistique, France: British Patent 800,250: August 20, 1958. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 100.0 | % | ~100 | % | DRUGBANK | |
| Volume of Distribution | 93.5 | L | 93.5 | L | normal,healthy; | DRUGBANK |
| Half-life | 2.5 | h | 2-3 | h | DRUGBANK | |
| Protein Binding | 30.0 | % | ~30 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for infants | 20.0 | mg/kg/day | 20 | mg/kg/day | PO, oral | Trecator | ethionamide | PDR |
| Max dose for children | 20.0 | mg/kg/day | 20 | mg/kg/day | PO, oral | Trecator | ethionamide | PDR |
| Max dose for children | 1000.0 | mg/day | 1 | g/day | PO, oral | Trecator | ethionamide | PDR |
| Max dose for adolescents | 20.0 | mg/kg/day | 20 | mg/kg/day | PO, oral | Trecator | ethionamide | PDR |
| Max dose for adolescents | 1000.0 | mg/day | 1 | g/day | PO, oral | Trecator | ethionamide | PDR |
| Max dose for adults | 1000.0 | mg/day | 1 | g/day | PO, oral | Trecator | ethionamide | PDR |
| Max dose for geriatric | 1000.0 | mg/day | 1 | g/day | PO, oral | Trecator | ethionamide | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1