DETAILS

Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID	DDPD00606
Drug Name	Cyclothiazide
Molecular Weight	389.878
Molecular Formula	C14H16ClN3O4S2
CAS Number	2259-96-3
SMILES	NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C1CC2CC1C=C2
External Links
	DRUGBANK	DB00606
	PubChem Compound	2910

Experimental Physicochemical Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Reference
Log P	1.95	-	1.95	-	YAMAZAKI,M ET AL. (1984)
Melting Point	229.5	℃	229-230	℃	Muller, E. and Hasspacher, K.; US. Patent 3,275,625; September 27,1966; assigned to Boehringer lngelheim GmbH, Germany.

Pharmacokinetic/ Toxicokinetic Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Reference
Toxicity LD50	10000.0	mg/kg	>10000	mg/kg	PO, oral; mouse;	DRUGBANK
Toxicity LD50	4000.0	mg/kg	>4000	mg/kg	PO, oral; Rattus, Rat;	DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1