Basic Information
| Drug ID | DDPD00595 |
|
| Drug Name | Oxytetracycline | |
| Molecular Weight | 460.434 | |
| Molecular Formula | C22H24N2O9 | |
| CAS Number | 79-57-2 | |
| SMILES | [H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)C4=C(C=CC=C4O)[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C | |
| External Links | ||
| DRUGBANK | DB00595 | |
| T3DB | T3D3953 | |
| PubChem Compound | 54675779 | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -0.9 | - | -0.9 | - | SANGSTER (1994) |
| Melting Point | 184.5 | ℃ | 184.5 | ℃ | PhysProp |
| Water Solubility | 313.0 | mg/L | 313 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| pKa | 3.27 | - | 3.27 | - | KORTUM,G ET AL (1961) |
| Log S | -3.14 | - | -3.14 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.12 | L/h/kg | 2 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 1.7 | L/kg | 1.7 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 10.0 | h | 10 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1