Basic Information
| Drug ID | DDPD00593 |
|
| Drug Name | Ethosuximide | |
| Molecular Weight | 141.1677 | |
| Molecular Formula | C7H11NO2 | |
| CAS Number | 77-67-8 | |
| SMILES | CCC1(C)CC(=O)NC1=O | |
| External Links | ||
| DRUGBANK | DB00593 | |
| T3DB | T3D2834 | |
| PubChem Compound | 3291 | |
| PDR | 1811 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.38 | - | 0.38 | - | ATKINSON,HC & BERG,EJ (1988) |
| Melting Point | 64.5 | ℃ | 64.5 | ℃ | PhysProp |
| Water Solubility | 39200.0 | mg/L | 39.2 | g/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 93.0 | % | 93 | % | PO, oral; | DRUGBANK |
| Half-life | 53.0 | h | 53 | h | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 1500.0 | mg/day | 1.5 | g/day | PO, oral | Zarontin Oral Solution | ethosuximide | PDR |
| Max dose for adolescents | 1500.0 | mg/day | 1.5 | g/day | PO, oral | Zarontin Oral Solution | ethosuximide | PDR |
| Max dose for adults | 1500.0 | mg/day | 1.5 | g/day | PO, oral | Zarontin Oral Solution | ethosuximide | PDR |
| Max dose for elderly | 1500.0 | mg/day | 1.5 | g/day | PO, oral | Zarontin Oral Solution | ethosuximide | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1