Basic Information

Drug ID DDPD00580 ...
Drug Name Valdecoxib
Molecular Weight 314.359
Molecular Formula C16H14N2O3S
CAS Number 181695-72-7
SMILES CC1=C(C(=NO1)C1=CC=CC=C1)C1=CC=C(C=C1)S(N)(=O)=O
External Links
DRUGBANK DB00580
PubChem Compound 119607
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 3.2 - 3.2 - DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 83.0 % 83 % DRUGBANK
Clearance 6.0 L/h 6.0 L/h Total clearance; PO, oral; DRUGBANK
Clearance 6.5 L/h 6.0-7 L/h patients; DRUGBANK
Clearance 0.0840 L/h/kg 1.4 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 86.0 L 86.0 L DRUGBANK
Volume of Distribution 0.75 L/kg 0.75 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 9.5 h 8-11 h DRUGBANK
Half-life 7.4 h 7.4 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Eliminate Route 5.0 % <5 % Urinary excretion; Faeces excretion; Unchanged drug; DRUGBANK
Protein Binding 98.0 % 98 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1